CLINICAL GENETICS

Surgery in cancer patient: Introduction, Types of surgery, Minimally Invasive Surgery (MIS)

Introduction: A team of professionals, including an oncologist, surgeon, and pathologist, work together to make the best diagnosis and treatment decisions for cancer patients. Surgery is the removal of the tumor and surrounding tissue during an operation. Surgery is the oldest and traditional type of cancer therapy, diagnosis, and remains an effective treatment for many […]

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Gene Therapy: Introduction, Types, Methods, Mechanism, Risks, Application

Introduction: Types: Ex Vivo- The term “ex vivo” means “outside of the living body”.  This technique is a medical procedure that involves removing of cells from the patient followed by genetically modified in a laboratory, using specialized approaches like adding a new gene to the cell or fixing a gene in a cell that is

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Chimeric Antigen Receptor (CAR)-T cell therapy: Introduction, components, mechanism, Side effects

Introduction: It is a type of cancer immunotherapy treatment that controls the ability of T cells (an immune cells) to detect and target specific antigen-expressing cells, including cancer cells. Moreover, this treatment involves genetic engineering of the T-cells of a patient to recognize and in order to attack cancer cells accordingly. In fact, the engineered

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In Vitro Fertilization (IVF)

In Vitro Fertilization (IVF): List of IVF & Fertility Center in Nepal

In vitro fertilization (IVF) is a medical procedure used to help people or couples who are having trouble getting pregnant. In vitro fertilization (IVF) includes fertilizing an egg with sperm outside the body in a laboratory dish, followed by the implantation of the fertilized embryo into the uterus. The primary objective of IVF is to

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Down Syndrome- Introduction, Prevalence, Risk factors, Diagnosis, Prevention

Down syndrome is a genetic condition caused by the presence of an extra copy of chromosome 21 in a person’s cells. This extra genetic material can cause developmental delays and physical characteristics such as distinctive facial features, low muscle tone, and intellectual disability.

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