Author name: sciencevivid

Sciencevivid is a specialized educational blog/website about several fields of biology (including microbiology, molecular biology, biochemistry, genetics, cell biology, and clinical genetics). Additionally, it provides the most recent and up-to-date news in the fields of technology, science, and research. It was founded on May 4, 2022, with the intention that undergraduate and graduate students (B.Sc, M.Sc, M.Phil, and Ph.D.) would have access to study notes and be able to comprehend it appropriately.

Extracellular vesicles (EVs): Introduction, Structure, Types, Isolation, Applications

Introduction to Extracellular Vesicles (EVs): Extracellular vesicles (EVs) are lipid bilayer membrane bound structures in extracellular fluids, which are secreted by all types of cells (either in normal or pathogenic conditions).  They are naturally released from the cell that are delimited by a lipid bilayer and cannot replicate. EVs are complex signals which can target […]

Extracellular vesicles (EVs): Introduction, Structure, Types, Isolation, Applications Read More »

NIPT (Non-Invasive Prenatal Testing): Introduction, Pregnancy Screening, Antenatal tests, Prenatal Test

What is NIPT? NIPT (Non-Invasive Prenatal Testing) is a prenatal blood test that is performed beginning around 10th weeks of pregnancy and can screen certain genetic conditions. It can be performed at any time after the 10th week of pregnancy. However, the ideal time is upto the 24th week. How does NIPT work? Our blood

NIPT (Non-Invasive Prenatal Testing): Introduction, Pregnancy Screening, Antenatal tests, Prenatal Test Read More »

Telomere Biology: Structure, Shelterin Complex, Hayflick Limit, Telomerases, Implications in Aging and Cancer

Telomere: Introduction Fig: Structure of telomerase and Shelterin Complex Structure and Composition The Shelterin Complex: Fig: The Role of the Components of Shelterin Complex in Telomeres and Telomerase Regulation Source: Clinical Interventions in Aging 2020:15 What is the Hayflick Limit? Hayflick outlines the three stages that typical cultivated cells go through. Telomerases: Telomerase is an

Telomere Biology: Structure, Shelterin Complex, Hayflick Limit, Telomerases, Implications in Aging and Cancer Read More »

Basis of Animal Classification and Helminthes: Platyhelminthes and Nemathelminthes – Morphology, Classification, and Medical Importance

Basis of Classification of Animals: Level of body organization Body symmetry Germ layers Diploblastic: Porifera and Coelenterata Triploblastic: Platyhelminthes to Chordata Body plan Coelom Body segmentation Introduction to Helminthes and Helminthology: Helminthology is the study of helminthes, which are animals that resemble worms. Helminthes are metazoans with well-developed organs, vermiform bodies. It comprises of phylum

Basis of Animal Classification and Helminthes: Platyhelminthes and Nemathelminthes – Morphology, Classification, and Medical Importance Read More »

Hepatitis A virus (HAV): Introduction, transmission, pathogenesis, clinical presentations and diagnosis

Introduction to Hepatitis A Virus (HAV): Hepatitis is the inflammation of liver cells of which viral infection is the most prevalent cause. Hepatitis A, Hepatitis B, Hepatitis C, Hepatitis D and Hepatitis E are the five primary hepatitis viruses.Hepatitis A virus (HAV), the etiologic agent of viral hepatitis A (infectious hepatitis), is the primary cause

Hepatitis A virus (HAV): Introduction, transmission, pathogenesis, clinical presentations and diagnosis Read More »

Chagas Disease (American Trypanosomiasis): Epidemiology, Morphological Forms, Life Cycle, Pathogenesis, and Laboratory Diagnosis

Introduction to Chagas Disease (American Trypanosomiasis): Morphological forms of Trypanosoma cruzi: Amastigote Amastigote is small, round, cytoplasmic in shape and is found in the cytoplasm of mammalian host cells. Binary fission separates the flagellum, which is either short or invisible. Epimastigote The epimastigote has an elongated shape and a noticeable flagellum. It is present in

Chagas Disease (American Trypanosomiasis): Epidemiology, Morphological Forms, Life Cycle, Pathogenesis, and Laboratory Diagnosis Read More »

Prion Diseases: Mechanism, Pathogenesis, and Human Disorders (CJD, Kuru, FFI)

Introduction to Prions: When a misfolded prion enters a healthy organism, it causes already-existing, correctly folded proteins to transform into the form of a misfolded prion. Therefore, other normal proteins misfold into prion form using prions as a template. Prion disorders, also known as transmissible spongiform encephalopathies, are a class of neurodegenerative illnesses that are

Prion Diseases: Mechanism, Pathogenesis, and Human Disorders (CJD, Kuru, FFI) Read More »

Fasciola hepatica: Introduction, clinical manifestation and diagnosis

Introduction to Fasciola hepatica: Fasciola hepatica is a hermaphroditic trematode with a complex life-cycle that includes an intermediate (snail) and definitive (mammalian) host. The earliest known trematode or fluke was F. hepatica.  However, it was initially found in sheep rather in humans. The disease, known as liver rot, is brought on by consuming metacercaria from

Fasciola hepatica: Introduction, clinical manifestation and diagnosis Read More »

Dengue Virus: Introduction, Morphology, Genome, Replication Cycle, and Pathogenesis

Introduction to Dengue Virus: Dengue is a mosquito-borne disease caused by the skin inoculation any of four antigenically different serotypes of the Dengue virus (DENV 1-4), characterized by wide spectrum of illness ranging from asymptomatic to severe forms. As the name ‘breakbone fever’, the patient complains of pain in the back, joint, muscles and the

Dengue Virus: Introduction, Morphology, Genome, Replication Cycle, and Pathogenesis Read More »

Clinical Specimen Selection, Collection, Transport, and Storage for Microbiological Diagnosis

General Considerations in Specimen Collection The vitals for specimen collection: Requisition The following details should be included in the laboratory request, or “lab slip”: Specimen selection and Collection: Timing of Specimen Collection: Transport of Clinical Specimens: Storage Guidelines for Different Specimen Types: Criteria for Specimen Rejection: SPECIMEN SELECTION POSSIBLE BACTERIA COLLECTION EQUIPMENT TRANSPORT Wounds, Abscesses

Clinical Specimen Selection, Collection, Transport, and Storage for Microbiological Diagnosis Read More »