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Extracellular vesicles (EVs): Introduction, Structure, Types, Isolation, Applications
Introduction to Extracellular Vesicles (EVs): Extracellular vesicles (EVs) are lipid bilayer membrane bound structures in extracellular fluids, which are secreted by all types of cells (either in normal or pathogenic conditions). They are naturally released from the cell that are delimited by a lipid bilayer and cannot replicate. EVs are complex signals which can target
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NIPT (Non-Invasive Prenatal Testing): Introduction, Pregnancy Screening, Antenatal tests, Prenatal Test
What is NIPT? NIPT (Non-Invasive Prenatal Testing) is a prenatal blood test that is performed beginning around 10th weeks of pregnancy and can screen certain genetic conditions. It can be performed at any time after the 10th week of pregnancy. However, the ideal time is upto the 24th week. How does NIPT work? Our blood
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Telomere Biology: Structure, Shelterin Complex, Hayflick Limit, Telomerases, Implications in Aging and Cancer
Telomere: Introduction Fig: Structure of telomerase and Shelterin Complex Structure and Composition The Shelterin Complex: Fig: The Role of the Components of Shelterin Complex in Telomeres and Telomerase Regulation Source: Clinical Interventions in Aging 2020:15 What is the Hayflick Limit? Hayflick outlines the three stages that typical cultivated cells go through. Telomerases: Telomerase is an
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Basis of Animal Classification and Helminthes: Platyhelminthes and Nemathelminthes – Morphology, Classification, and Medical Importance
Basis of Classification of Animals: Level of body organization Body symmetry Germ layers Diploblastic: Porifera and Coelenterata Triploblastic: Platyhelminthes to Chordata Body plan Coelom Body segmentation Introduction to Helminthes and Helminthology: Helminthology is the study of helminthes, which are animals that resemble worms. Helminthes are metazoans with well-developed organs, vermiform bodies. It comprises of phylum
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Hepatitis A virus (HAV): Introduction, transmission, pathogenesis, clinical presentations and diagnosis
Introduction to Hepatitis A Virus (HAV): Hepatitis is the inflammation of liver cells of which viral infection is the most prevalent cause. Hepatitis A, Hepatitis B, Hepatitis C, Hepatitis D and Hepatitis E are the five primary hepatitis viruses.Hepatitis A virus (HAV), the etiologic agent of viral hepatitis A (infectious hepatitis), is the primary cause
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Chagas Disease (American Trypanosomiasis): Epidemiology, Morphological Forms, Life Cycle, Pathogenesis, and Laboratory Diagnosis
Introduction to Chagas Disease (American Trypanosomiasis): Morphological forms of Trypanosoma cruzi: Amastigote Amastigote is small, round, cytoplasmic in shape and is found in the cytoplasm of mammalian host cells. Binary fission separates the flagellum, which is either short or invisible. Epimastigote The epimastigote has an elongated shape and a noticeable flagellum. It is present in
