The Philadelphia chromosome is a result of a reciprocal translocation between the long arms of chromosomes 9 and 22 t (9;22) (q34; q11). It was given the name of the town where it was found.
The Philadelphia Chromosome- Leukemia, Translocation, Diagnostic Tests Read More »
The primary goal of extracting nucleic acids is for downstream applications such as PCR, sequencing, cloning, genetic analysis or forensic applications.
Nucleic Acid (DNA/RNA)- Detection, Purity, Quantitation, Applications Read More »
Transfection is a method for introducing foreign nucleic acids
Transfection-Principle, Methods, Applications Read More »
In electroporation, an electric current is applied to a living surface, such as the skin or a cell membrane that open pores or channels through which is used to introduce foreign DNA or other molecules into cells.
Electroporation-Definition, Types, Process, Applications Read More »
A simple blood sample or other bodily fluid can be used as a diagnostic test called a liquid biopsy, which gives doctors an easy and non-invasive alternative to surgical biopsies for learning more about tumors.
Liquid Biopsy- Definition, Procedures, Advantages Read More »
Introduction: History: The concept of digital PCR (dPCR) was first described in a 1996 paper by Scherer and colleagues, who proposed using microfluidic devices to partition a sample into thousands of small compartments and perform PCR on each compartment. The first commercial dPCR instrument, the Bio-Rad iCycler iQ, was introduced in 2003. Since then, dPCR
Digital PCR: Definition, Principle, Instrumentation, Steps, Applications Read More »
Biosafety cabinets are specialized designed laboratory equipment that provide a barrier between the user and the materials being handled inside the cabinets.
Biosafety Cabinet (BSC)-Types, Features, Handling, Applications Read More »
Introduction: Mechanism: Initiation: Autophagy is initiated by the activation of autophagy-related genes, which leads to the formation of a double-membraned vesicle called the autophagosome. Nucleation: The autophagosome is formed through a process called nucleation, which involves the assembly of a protein complex called the phagophore assembly site (PAS). The PAS consists of several proteins, including
Autophagy- Definition, Types, Mechanism, Regulations, Diseases Read More »
Introduction: Cell injury is a term used to describe any type of damage or harm that occurs to a cell. This can be caused by a variety of factors, including physical damage, chemical damage, or biological damage. Cell injury can range from mild to severe, and it can result in a variety of changes in
Cell injury- Introduction, Causes, Types, Mechanism, Morphology Read More »
lncRNA-miRNA Gene Expression Regulation in Cancer
RNA Splicing- Definition, Process, Mechanism, Types, Errors, Importance Read More »
