Introduction to Cancer Metastasis: Metastasis is the word for the growth of secondary cancers in an area of the body distant from the initial primary cancer. Cancer treatment is challenging because of metastases. If the treatment works in one region, there is a secondary spread in other regions. The two main causes of cancer death

Introduction to Signal Transduction and Cancer: A cell of our body depends upon the signal transduction pathway to carry out different types of cell processes at the right moment in time to basically produce physiological responses to certain types of external stimuli.  Now, even though signal transduction is very important to the functionality of our

Introduction to Cell Transformation: The process of eukaryotic cells turning to cancerous cells from the normal cells is known as cell transformation. In cancer cell transformation there are few different modifications. In basic, there is a balance between cell growth and cell death. There are several pathways in the body that dictate the cell to

Introduction: Receptor tyrosine kinases (RTKs) are plasma membrane receptor glycoprotein in nature with enzymatic activity. They are a group of 90 enzymes capable of selectively phosphorylating amino acid tyrosine residue in various substrates which leads to conformational alteration of that protein and typically activates that protein.  They are important mediators of the signaling that mediate cell

Mechanism of induction of cancer: It is a gradual multistep process involving many generations of cells. The cancer cells are genetically and phenotypically transformed cells having phenotypic features of malignancy like excessive growth, invasiveness, and distant metastasis. Normal cell growth is genetically controlled by four different types of regulatory control genes. The abnormality in these

Tumor suppressor Genes: Introduction Tumor suppressor genes code for protein which function to control cell division and ensure that it only occurs when necessary. It is also recognized as a guardian of gene. Tumor suppressor genes code for proteins involved in preventing cell cycle progression known as gate keepers and proteins involved in repairing DNA