Whole genome sequencing (WGS) is a comprehensive method that detects nearly all DNA alterations by sequencing both the protein-coding and non-coding components of the genome.
Whole Genome Sequencing (WGS)- Introduction, workflow, Pipelines, Applications Read More »
Metagenomics is a field of study that involves the sequencing and analysis of genetic material from environmental samples, such as soil, water, air, or the human body.
Metagenomics-Definition, Steps, Process, tools, Applications Read More »
FISH is a simple technique that involves hybridizing a DNA probe to its complementary sequence on chromosomal preparations that have been previously placed on slides.
FISH- Definition, Principle, Probes, Procedure, Applications Read More »
Bioinformatics is the field of science that combines biology, computer science, and information technology. It involves the use of computational techniques to analyze large amounts of biological data.
Bioinformatics – Tools, software, Databases, Programmes, Models Read More »
Sanger sequencing is a method of DNA sequencing that was developed by Frederick Sanger in the 1970s. It is a chain termination method that uses modified nucleotides, called dideoxynucleotides, to stop the synthesis of a growing DNA strand.
Sanger Sequencing- Principle, Protocol, Applications, Limitations Read More »
The Philadelphia chromosome is a result of a reciprocal translocation between the long arms of chromosomes 9 and 22 t (9;22) (q34; q11). It was given the name of the town where it was found.
The Philadelphia Chromosome- Leukemia, Translocation, Diagnostic Tests Read More »
The primary goal of extracting nucleic acids is for downstream applications such as PCR, sequencing, cloning, genetic analysis or forensic applications.
Nucleic Acid (DNA/RNA)- Detection, Purity, Quantitation, Applications Read More »
In electroporation, an electric current is applied to a living surface, such as the skin or a cell membrane that open pores or channels through which is used to introduce foreign DNA or other molecules into cells.
Electroporation-Definition, Types, Process, Applications Read More »
Introduction: History: The concept of digital PCR (dPCR) was first described in a 1996 paper by Scherer and colleagues, who proposed using microfluidic devices to partition a sample into thousands of small compartments and perform PCR on each compartment. The first commercial dPCR instrument, the Bio-Rad iCycler iQ, was introduced in 2003. Since then, dPCR
Digital PCR: Definition, Principle, Instrumentation, Steps, Applications Read More »
lncRNA-miRNA Gene Expression Regulation in Cancer
RNA Splicing- Definition, Process, Mechanism, Types, Errors, Importance Read More »
