The prevalence of genetic disorders is high in Nepal due to the high rate of consanguineous marriages, limited healthcare resources, and inadequate genetic counselling services.
Molecular Genetic Testing in Nepal: Prevalence and Resources Read More »
Chromosomal analysis is a widely used technique in diagnosing chromosome instability and rearrangements that contribute to genetic diseases and cancer.
Protocol of Human Lymphocyte Culture and Chromosome Analysis Read More »
The Philadelphia chromosome is a result of a reciprocal translocation between the long arms of chromosomes 9 and 22 t (9;22) (q34; q11). It was given the name of the town where it was found.
The Philadelphia Chromosome- Leukemia, Translocation, Diagnostic Tests Read More »
Introduction: Principle: Types: Methods: There are several different methods of NGS, each with its own strengths and limitations. These are just a few examples of the many methods of NGS that are available. The choice of method depends on the specific research question and the type of data that is needed. Steps: Sequencing data can
NGS- Definition, Principle, Types, Methods, Step, Applications Read More »
Introduction: Procedure: Amniocentesis is typically performed between the 15th and 20th weeks of pregnancy. The procedure is usually done in a doctor’s office or clinic, and takes about 15-20 minutes. Here is an overview of the steps involved in an amniocentesis: Preparation: The patient will be asked to lie on an exam table on the
Amniocentesis- Definition, Procedure, Risks, Benefits Read More »
Introduction: What Is CRISPR-Cas9? CRISPR-Cas9 as a Adaptive Immune: Invading bacteriophages are protected against bacteria by the CRISPR-Cas9 system. As spacers within the bacterial genome’s CRISPR locus, Cas1 and Cas2 incorporate a brief section of the viral genome after infection. The CRISPR locus is expressed as pre-CRNA and tracrRNA upon re-infection with the same virus.
CRISPR-Cas9- Introduction, Mechanism, Diagnosis, Applications Read More »
DNA fingerprinting, also known as DNA profiling or genetic fingerprinting, is a forensic technique that analyzes specific regions of an individual’s DNA to create a unique genetic profile, enabling the identification and comparison of individuals based on their DNA patterns, which has widespread applications in criminal investigations, paternity testing, and genetic research.
DNA fingerprinting- Definition, Principle, Steps, Applications Read More »
Mutation is a fundamental process in genetics, referring to a permanent alteration in the DNA sequence, which can lead to genetic variation and, in certain cases, contribute to the development of diseases or provide the basis for evolution and adaptation in living organisms.
Mutation- Introduction, Mutagens, Effects, Classification Read More »
Prenatal testing encompasses a range of medical procedures and tests conducted during pregnancy to assess the health and development of the fetus, enabling early detection of genetic disorders, and chromosomal abnormalities.
Prenatal testing- Birth defects, Types, Current practice Read More »
