Nucleic acids are complex biomolecules that serve as the building blocks of genetic information, playing a crucial role in storing, transmitting, and expressing the genetic instructions necessary for the functioning and development of all living organisms.
Nucleic acid (DNA, RNA) – Definition, Class, Function, Application Read More »
DNA extraction is a fundamental laboratory procedure that involves isolating DNA from cells or tissues, enabling researchers to study and analyze genetic information for a wide range of applications, from medical diagnostics to forensic investigations and genetic research.
DNA extraction- Introduction, Methods, History, Types, Confirmation, Detection Read More »
Mutation is a fundamental process in genetics, referring to a permanent alteration in the DNA sequence, which can lead to genetic variation and, in certain cases, contribute to the development of diseases or provide the basis for evolution and adaptation in living organisms.
Mutation- Introduction, Mutagens, Effects, Classification Read More »
Introduction: Glycolysis is a cytoplasmic pathway of both prokaryotic and eukaryotic cells that breaks down glucose into two three-carbon compounds and generates energy. It is also named as Embden–Meyerhof–Parnas (EMP) pathway. Glycolysis is the first step in the breakdown of glucose to extract energy for cellular metabolism. Nearly all living organisms carry out glycolysis as part of
Glycolysis- Occurrence, Stages, Regulations, Significance Read More »
Background: Nepal has an incredible geographic diversity with an altitude ranging from 50m to highest peak in the world (Mt. Everest, 8848m) from sea level and is topographically divided into three regions: The Terai, the Hilly and the Himalayan regions. The Himalaya and its foothills make up the northern border of the country and represent
High altitude adaptations in Sherpa community of Nepal Read More »
Epigenetics refers to the study of heritable changes in gene expression or cellular phenotype that occur without alterations to the DNA sequence itself
Epigenetics- Introduction, Principle, Significance Read More »
Introduction: History: The HGP has an ultimate goal of identifying and locating the positions of all genes in the human body. A researcher named Renato Dulbecco first suggested the idea of such a project while the U.S. Department of Energy (DOE) was also considering the same project because issues related to radiation and chemical exposure
Human genome project- Introduction, Goals, Applications Read More »
Cell-free DNA (cfDNA) refers to small fragments of DNA that are present in bodily fluids, such as blood, urine, saliva, and cerebrospinal fluid
Cell-free DNA (cfDNA)-Introduction, Properties, Clinical Applications Read More »
Prenatal testing encompasses a range of medical procedures and tests conducted during pregnancy to assess the health and development of the fetus, enabling early detection of genetic disorders, and chromosomal abnormalities.
