Author name: sciencevivid

Sciencevivid is a specialized educational blog/website about several fields of biology (including microbiology, molecular biology, biochemistry, genetics, cell biology, and clinical genetics). Additionally, it provides the most recent and up-to-date news in the fields of technology, science, and research. It was founded on May 4, 2022, with the intention that undergraduate and graduate students (B.Sc, M.Sc, M.Phil, and Ph.D.) would have access to study notes and be able to comprehend it appropriately.

Cancer and Signal Transduction: The Role of EGF Pathway in Tumor Growth and Its Regulation

Introduction to Signal Transduction and Cancer: A cell of our body depends upon the signal transduction pathway to carry out different types of cell processes at the right moment in time to basically produce physiological responses to certain types of external stimuli.  Now, even though signal transduction is very important to the functionality of our […]

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Cell Transformation: Mechanisms, Genetic Mutations, and Cancer Progression

Introduction to Cell Transformation: The process of eukaryotic cells turning to cancerous cells from the normal cells is known as cell transformation. In cancer cell transformation there are few different modifications. In basic, there is a balance between cell growth and cell death. There are several pathways in the body that dictate the cell to

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Receptor tyrosine kinases (RTKs): Introduction, Structure, Tyrosine Kinase Inhibitors (TKIs), RTKs dysregulation and cancer

Introduction: Receptor tyrosine kinases (RTKs) are plasma membrane receptor glycoprotein in nature with enzymatic activity. They are a group of 90 enzymes capable of selectively phosphorylating amino acid tyrosine residue in various substrates which leads to conformational alteration of that protein and typically activates that protein.  They are important mediators of the signaling that mediate cell

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Determination of Acid Value of Fats and Oils: A Comparative Analysis of Cooked and Uncooked Oil

Objective: To determine the acid value of given fat sample Theory: Acid value is defined as the number of milligrams of potassium or sodium hydroxide that is required to neutralize the free fatty acids in 1 gram of fats or oil. It is a measure of the number of carboxylic acid group in a chemical

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Molecular basis of cancer: Oncogene,  Tumor suppressor Genes, Carcinogenesis, Mechanism of Action of Oncogenes

Mechanism of induction of cancer: It is a gradual multistep process involving many generations of cells. The cancer cells are genetically and phenotypically transformed cells having phenotypic features of malignancy like excessive growth, invasiveness, and distant metastasis. Normal cell growth is genetically controlled by four different types of regulatory control genes. The abnormality in these

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Tumor Suppressor Genes and Oncogenes: Introduction, p53 gene, RB gene and Two hit Hypothesis

Tumor suppressor Genes: Introduction Tumor suppressor genes code for protein which function to control cell division and ensure that it only occurs when necessary. It is also recognized as a guardian of gene. Tumor suppressor genes code for proteins involved in preventing cell cycle progression known as gate keepers and proteins involved in repairing DNA

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Isolation of Mitochondria

Aim: To isolate mitochondria from the given sample Objective: The isolation of mitochondria is useful in order to study and explore fundamental processes including mitochondrial respiration, metabolic activity, protein import, membrane fusion, protein complex assembly, as well as interactions of mitochondria with the cytoskeleton, nuclear encoded mRNAs, and other organelles.  Principle: The nucleus has two

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Cell cycle, Checkpoints, Cyclins and Its Types: Introduction, External and Internal signals of cell cycle control

Introduction to Cell Cycle Regulation: Cell division is a very crucial phenomenon for normal growth, development and maintenance. But in a body of eukaryotes organisms such as humans, the rate of timing of cell division varies on the type of cells. For e.g., skin cells divide frequently throughout life time. However, specialized cells such as

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Surgery in cancer patient: Introduction, Types of surgery, Minimally Invasive Surgery (MIS)

Introduction: A team of professionals, including an oncologist, surgeon, and pathologist, work together to make the best diagnosis and treatment decisions for cancer patients. Surgery is the removal of the tumor and surrounding tissue during an operation. Surgery is the oldest and traditional type of cancer therapy, diagnosis, and remains an effective treatment for many

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Oparin-Haldane theory: Modern theory of the origin of life, Miller and Urey’s Experiment

Background: Different scientists and philosophers have put forwards different explanation of origin of life on earth from time to time. Some of the most popular hypotheses about the origin of life include the following: Introduction:  Stages:  This theory possesses three stages: Chemogeny Biogeny Cognogeny Oxygen revolution: Early atmosphere transform from reducing to oxidising and the

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