Author name: sciencevivid

Sciencevivid is a specialized educational blog/website about several fields of biology (including microbiology, molecular biology, biochemistry, genetics, cell biology, and clinical genetics). Additionally, it provides the most recent and up-to-date news in the fields of technology, science, and research. It was founded on May 4, 2022, with the intention that undergraduate and graduate students (B.Sc, M.Sc, M.Phil, and Ph.D.) would have access to study notes and be able to comprehend it appropriately.

Cytokine Storm Syndrome (CSS) in COVID-19: Mechanisms, Clinical Impact, and Therapeutic Insights

Introduction- COVID-19 and Global Health Impact: One of the most pressing global health issues that humanity has encountered since World War II is the COVID-19 pandemic. With the exception of Antarctica, the virus has spread to every continent since it first appeared in Asia in 2020. Medical professionals and researchers were investigating the underlying mechanism […]

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Cyclospora cayetanensis: Lifecycle, Pathogenesis, Laboratory Detection, and Public Health Strategies

Introduction: Cyclospora is an intracellular, single-celled sporozoan with a diameter of around 8.6 μm. When someone consumes food or water contaminated with the parasite, they become infected. It cannot transmit from one person to another as the oocysts in the faecal matter require a certain days and temperature for sporulation and becoming infective. The infected

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Total Quality Management in microbiology laboratory

Introduction to Total Quality Management (TQM) in a microbiology laboratory: There are all the activities that effort to establish and maintain continued improvement in lab to do what it is intended to do i.e. clinical relevance achievement by delivery of high quality services to customer aiding in patient management. Lab organization: Organization is one of

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Potential Risks of Using Continuous Cell Lines (CCLs) in Viral Vaccine Development

Introduction to Cell Substrates in Vaccine Production: Cell substrates have been a never-ending source of concern about the potential for transmitting infectious diseases and/or cancer. The initial key decision in selecting cell substrates for vaccine production was to minimize the risk of cancer transmission through live viral vaccines. This led to the restriction of acceptable

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Immunodeficiency: Introduction, brief account of life cycle of HIV and immunodeficiency during HIV infection

Introduction to Immunodeficiency: Life Cycle of HIV: HIV infection is usually transmitted vertically from an infected mother to the baby via the placenta or by breastfeeding. Horizontally, HIV can be transmitted through activities like non-screened blood transplantation, use of infected needle sticks, needle stick injury, and unsafe sexual contact.  So, the virus can be transmitted

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Ascariasis: Introduction, pathogenesis, diagnosis, prevention and control

Introduction: Ascaris lumbricoides belongs to class Phasmida of Phylum Aschelminthes or Nemathelminthes. It is commonly called a roundworm, attributed to its worm-like morphology. Because A. lumbricoides eggs can withstand a variety of environmental circumstances, a large number of eggs are generated per female worm, and inadequate sanitary conditions are common, particularly in developing and undeveloped

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Comprehensive Guide to Organizing a Clinical Microbiology Laboratory: Design, Management, and ISO 15189 Compliance

Introduction to Clinical Microbiology Laboratory Organization: A clinical microbiology lab performs analytical tests on human body substances for disease diagnosis, prevention and aids patient management for promotion of good health. Organization means an orderly structure making arrangements for achievement of purpose. In microbiology lab, the purpose is clinical relevance i.e., promotion of patient’s health.  Key

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Protein Secretion in Bacteria: Introduction, Sec and Tat Pathways, Signal Recognition Particle (SRP) Pathway

Introduction to Protein Secretion in Bacteria: Like all other organisms, bacteria have all the necessary cell structures that ensure their survival and proper functioning. The protective cell envelope can be two or three membranes, depending on the nature of the bacteria. Bacteria are protected from the environment by one or two membranes that prevent the

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Conventional and rapid methods in the laboratory diagnosis of pyrexia of unknown origin

Introduction to Pyrexia of Unknown Origin (PUO): Pyrexia of unknown origin (PUO) is a temperature above 38.3 degrees Celsius, lasting more than 3 weeks, and there is failure to reach a diagnosis despite a week of inpatient investigation.  PUO could be classic PUO (temperature >38.3 degrees Celsius for more than 3 weeks and evaluation of

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Biosecurity and Biosafety: Framework, Levels, Protocols, and Regulations

Introduction to Biosecurity and Biosafety: Biosecurity is the prevention of misuse, loss, theft and unauthorized access, and intentional release of harmful agents like pathogens, their toxins, and the equipment involved in doing so. The Biological and Toxin Weapons Convention was formed in 1975 to address the bad use of bioweapons. The biosecurity functions are at

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