FISH is a simple technique that involves hybridizing a DNA probe to its complementary sequence on chromosomal preparations that have been previously placed on slides.
FISH- Definition, Principle, Probes, Procedure, Applications Read More »
Preimplantation Genetic Screening (PGS) is a laboratory procedure that is performed on embryos during in-vitro fertilization (IVF) to determine if they have the correct number of chromosomes.
Preimplantation genetic screening (PGS)- Technique, Applications, Limitations, PGD Read More »
Chromosomal analysis is a widely used technique in diagnosing chromosome instability and rearrangements that contribute to genetic diseases and cancer.
Protocol of Human Lymphocyte Culture and Chromosome Analysis Read More »
Introduction: Causes of Infertility: Infertility is a complex issue that can have various causes, both in males and females. Here are some common causes of infertility: Female Factors Male Factors Unexplained Infertility In some cases, the cause of infertility cannot be identified despite thorough medical evaluations. Unexplained infertility is diagnosed when all standard tests and
IVF- Definition, Prevalence, Procedure, Risks, Medications  Read More »
Introduction: Infertility is the inability to conceive after a certain period of time trying to become pregnant (usually one year). It can be caused by a variety of factors, including hormonal imbalances, structural problems with the reproductive organs, and certain medical conditions. In some cases, the cause of infertility is unknown. Prevalence: Types: It’s important
Infertility- Definition, Prevalence, Types, Causes, Diagnosis, Treatment Read More »
Introduction: Types of Serum marker: Maternal serum marker tests are blood tests that are used to screen for certain chromosomal abnormalities or birth defects in a developing fetus. The tests measure the levels of specific substances, known as markers, in the blood of the pregnant woman. Elevated levels of certain markers can indicate an increased
Maternal Serum Marker Test- Definition, Types, Trimester, Risks, Benefits Read More »
Introduction: Procedure: Amniocentesis is typically performed between the 15th and 20th weeks of pregnancy. The procedure is usually done in a doctor’s office or clinic, and takes about 15-20 minutes. Here is an overview of the steps involved in an amniocentesis: Preparation: The patient will be asked to lie on an exam table on the
Amniocentesis- Definition, Procedure, Risks, Benefits Read More »
Molecular diagnostics tests play a crucial role in modern medicine, utilizing advanced techniques such as PCR, NGS, and gene expression analysis to analyze DNA and RNA for genetic disorders, infectious diseases, oncology, and pharmacogenetics.
Molecular Diagnostics Tests- Definition, Principle, Types, Instruments Read More »
Introduction: What Is CRISPR-Cas9? CRISPR-Cas9 as a Adaptive Immune: Invading bacteriophages are protected against bacteria by the CRISPR-Cas9 system. As spacers within the bacterial genome’s CRISPR locus, Cas1 and Cas2 incorporate a brief section of the viral genome after infection. The CRISPR locus is expressed as pre-CRNA and tracrRNA upon re-infection with the same virus.
CRISPR-Cas9- Introduction, Mechanism, Diagnosis, Applications Read More »
Cell-free DNA (cfDNA) refers to small fragments of DNA that are present in bodily fluids, such as blood, urine, saliva, and cerebrospinal fluid
Cell-free DNA (cfDNA)-Introduction, Properties, Applications Read More »
