The Philadelphia chromosome is a result of a reciprocal translocation between the long arms of chromosomes 9 and 22 t (9;22) (q34; q11). It was given the name of the town where it was found.
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Introduction: History: The concept of digital PCR (dPCR) was first described in a 1996 paper by Scherer and colleagues, who proposed using microfluidic devices to partition a sample into thousands of small compartments and perform PCR on each compartment. The first commercial dPCR instrument, the Bio-Rad iCycler iQ, was introduced in 2003. Since then, dPCR
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Molecular diagnostics tests play a crucial role in modern medicine, utilizing advanced techniques such as PCR, NGS, and gene expression analysis to analyze DNA and RNA for genetic disorders, infectious diseases, oncology, and pharmacogenetics.
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Discover the power of reverse transcription polymerase chain reaction (RT-PCR), a versatile molecular biology technique used to amplify and detect RNA molecules. Explore the principles behind RT-PCR, including reverse transcription of RNA into complementary DNA (cDNA) and subsequent PCR amplification.
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