Transcription factors are proteins that regulate gene expression by controlling the rate at which DNA is transcribed into RNA and play a crucial role in cellular processes.
Post-transcriptional modifications refer to a variety of molecular alterations that occur to RNA molecules after transcription, playing crucial roles in gene expression regulation.
Post-transcriptional modifications (PTMs)- Steps, Regulations, Processing Read More »
DNA transcription is the process in which genetic information encoded in DNA is used to synthesize an RNA molecule, known as messenger RNA (mRNA), through the activity of RNA polymerase, enabling the transfer of genetic instructions from the DNA to the cellular machinery for protein synthesis.
DNA Transcription (RNA Synthesis) – Enzymes, Steps, RNA Processing Read More »
The central dogma of molecular biology is a fundamental principle stating that genetic information flows from DNA to RNA through the process of transcription, and then from RNA to proteins through the process of translation, forming the basis of gene expression and protein synthesis.
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Introduction to Cancer Metastasis: Metastasis is the word for the growth of secondary cancers in an area of the body distant from the initial primary cancer. Cancer treatment is challenging because of metastases. If the treatment works in one region, there is a secondary spread in other regions. The two main causes of cancer death
Cancer Metastasis : Stages, Molecular Mechanisms, EMT in Tumor Spread Read More »
Introduction to Signal Transduction and Cancer: A cell of our body depends upon the signal transduction pathway to carry out different types of cell processes at the right moment in time to basically produce physiological responses to certain types of external stimuli. Now, even though signal transduction is very important to the functionality of our
Introduction to Cell Transformation: The process of eukaryotic cells turning to cancerous cells from the normal cells is known as cell transformation. In cancer cell transformation there are few different modifications. In basic, there is a balance between cell growth and cell death. There are several pathways in the body that dictate the cell to
Cell Transformation: Mechanisms, Genetic Mutations, and Cancer Progression Read More »
Introduction: Receptor tyrosine kinases (RTKs) are plasma membrane receptor glycoprotein in nature with enzymatic activity. They are a group of 90 enzymes capable of selectively phosphorylating amino acid tyrosine residue in various substrates which leads to conformational alteration of that protein and typically activates that protein. They are important mediators of the signaling that mediate cell
Mechanism of induction of cancer: It is a gradual multistep process involving many generations of cells. The cancer cells are genetically and phenotypically transformed cells having phenotypic features of malignancy like excessive growth, invasiveness, and distant metastasis. Normal cell growth is genetically controlled by four different types of regulatory control genes. The abnormality in these
Tumor suppressor Genes: Introduction Tumor suppressor genes code for protein which function to control cell division and ensure that it only occurs when necessary. It is also recognized as a guardian of gene. Tumor suppressor genes code for proteins involved in preventing cell cycle progression known as gate keepers and proteins involved in repairing DNA
